In this webinar, the authors review the initiation and evolution of Pan-Africanism, the contributions of its chief proponents and both its historical and contemporary institutional manifestations. The multi-sectoral benefits of continental unification are articulated, as well as the challenges and constraints that must be resolved in order to enable such unification to achieve fruition. The alternative paths toward bridging collaborative engagement among continental Africans and Africans in the diaspora are addressed, including interdisciplinary research, collective political action, intensified involvement with the African Union, with regional collectivities, multi-lateral humanitarian and philanthropic organizations and an accelerated global participation in implementing the United Nations Sustainable Development Goals, particularly as relates to African countries and to vulnerable African diasporadic communities in Europe, Middle East, Asia, North America, Central & South America and the Caribbean. Finally, the anticipated impacts of a Pan-African transformation of individuated sectors are examined, e.g. international diplomacy, foreign direct investment & trade management, public health, biogenic & anthropogenic disaster resilience, armed conflict minimization, crime and corruption control, environmental sustainability, biodiversity protection, climate change mitigation, primary, secondary and higher education expansion, gender equality, immigration rationalization, enhanced employment opportunities, increased religious tolerance, as well as both food and water security.